Cell transplantation in Diabetes

Allo-transplantation and Auto-transplantation are the two types of pancreatic islet cell transplantation. Allo transplantation is a method where islets from pancreas of a deceased donor are purified and transferred to another person. This procedure is performed in certain patients with type 1 diabetes whose glucose levels in the blood are difficult to control. The aim of such transplantation is to normalize blood glucose levels with or without insulin injections and to eliminate unawareness of hypoglycaemia. Auto transplantation is performed by surgical removal of the entire pancreas, followed by purification of the islets and infusion into the patients’ liver.